00279nam a2200097Ia 4500008004100000022001400041040001100055245004000066260006400106300001100170251112s9999||||xx |||||||||||||| ||und||  a0028-4793  aCNCLSA 4aThe New England Journal of Medicine  cJanuary-Frbruary, 2009bMassachusetts Medical SocietyaU.K.  bV. 360