00270nam a2200097Ia 4500008004100000040001100041245004200052260005400094300001400148300001000162251112s9999||||xx |||||||||||||| ||und||  aCNCLSA 4aThe Journal of Clinical Investigation  cSeptember/October, 2005bpergamon pressaNew York  aP. 1-1110  bV. 15